STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB94274.1Glucokinase; InterPro IPR004654:IPR000600; COGs: COG1940 Transcriptional regulator/sugar kinase; KEGG: mta:Moth_0832 glucokinase; SPTR: Glucokinase; PFAM: ROK family protein; TIGRFAM: glucokinase, ROK family. (317 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.889
fbp
Fructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.865
SMB91467.1
Transketolase subunit A; InterPro IPR005474; COGs: COG3959 Transketolase N-terminal subunit; KEGG: mta:Moth_0236 transketolase subunit A; SPTR: Transketolase subunit A; PFAM: Transketolase domain-containing protein.
    
 0.860
SMB91474.1
Transketolase subunit B; InterPro IPR005475:IPR005476; COGs: COG3958 Transketolase C-terminal subunit; KEGG: mta:Moth_0237 transketolase subunit B; SPTR: Transketolase subunit B; PFAM: Transketolase central region; Transketolase domain-containing protein.
     
 0.858
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.852
SMB90877.1
InterPro IPR001250; COGs: COG1482 Phosphomannose isomerase; KEGG: ttr:Tter_0465 mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase.
 
 
 0.828
SMB99292.1
Nucleotidyltransferase; InterProIPR018357:IPR005835:IPR001451:IPR005844:IPR 005845; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); KEGG: mta:Moth_1925 nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
  
 
 0.805
nanE
N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 
 0.786
SMB91406.1
Phosphoglucomutase, alpha-D-glucose phosphate-specific; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 005841; COGs: COG1109 Phosphomannomutase; KEGG: mta:Moth_0221 phosphoglucomutase; SPTR: Phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase.
 
 
 0.784
SMB94279.1
Acetylornithine deacetylase; InterPro IPR002933:IPR011650:IPR001261; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; KEGG: tte:TTE0388 acetylornithine deacetylase; SPTR: Peptidase family M20/M25/M40; PFAM: peptidase M20; peptidase dimerisation domain protein.
       0.773
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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