STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SMB94393.1RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa)    
Predicted Functional Partners:
SMB94381.1
Stage II sporulation protein GA (sporulation sigma-E factor processing peptidase); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
  
 0.950
SMB94403.1
Stage II sporulation protein R; InterPro IPR014202; KEGG: mta:Moth_0854 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Sporulation stage II protein R; TIGRFAM: stage II sporulation protein R.
 
   
 0.942
SMB94405.1
Sporulation protein, YlmC/YmxH family; InterPro IPR014238:IPR007903; KEGG: mta:Moth_0855 PRC-barrel; SPTR: PRC-barrel; PFAM: PRC-barrel domain protein; TIGRFAM: sporulation protein, YlmC/YmxH family.
 
     0.914
SMC00071.1
Serine phosphatase; InterPro IPR010822:IPR001932; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; KEGG: mta:Moth_0103 serine phosphatase; SPTR: Serine phosphatase; SMART: protein phosphatase 2C domain protein; PFAM: Stage II sporulation protein E; PRIAM: Phosphoprotein phosphatase.
  
  
 0.890
SMB94389.1
RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
0.877
SMB98305.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
  
 0.819
SMB89514.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D; InterPro IPR014208:IPR018356; KEGG: adg:Adeg_0086 sporulation transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; SPTR: Transcription regulator of sigma-E/sigma-K-dependent gene spoIIID.
  
  
 0.817
SMB89477.1
Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: hmo:HM1_0719 stage V sporulation protein T, AbrB family transcriptional regulator; SPTR: Stage v sporulation protein t, abrb family transcriptional regulator; PFAM: SpoVT/AbrB domain-containing protein; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family.
  
   
 0.806
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.805
SMB98446.1
Sporulation protein YtfJ; InterPro IPR014229; COGs: COG3874 conserved hypothetical protein; KEGG: mta:Moth_1358 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Sporulation protein YtfJ; TIGRFAM: sporulation protein YtfJ.
  
   
 0.794
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.