STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (359 aa)    
Predicted Functional Partners:
SMB97306.1
Adenosylcobinamide kinase; InterPro IPR003203; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; KEGG: dae:Dtox_3094 adenosylcobinamide-phosphateguanylyltransferase; SPTR:Adenosylcobinamide-phosphateguanylyltransferas e; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase.
 
 0.998
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.971
cbiA
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.967
SMB97359.1
Phosphoglycerate mutase; InterPro IPR001345:IPR017578:IPR003094:IPR013078; COGs: COG0406 Fructose-2 6-bisphosphatase; KEGG: mta:Moth_1105 phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase.
 
 0.959
SMB98267.1
InterPro IPR012809:IPR003339; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; KEGG: cobalt ABC transporter, inner membrane subunit CbiQ; SPTR: Cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ.
  
  
 0.934
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.932
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.908
cbiA-2
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.895
SMB97353.1
Threonine kinase; InterPro IPR012363:IPR006204; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; KEGG: mta:Moth_1103 GHMP kinase; SPTR: GHMP kinase; PFAM: GHMP kinase.
  
  
 0.860
SMB95150.1
Predicted metal-binding protein; InterPro IPR013217:IPR019271; COGs: COG5423 metal-binding protein; KEGG: protein of unknown function DUF2284, metal-binding protein; SPTR: O-methyltransferase, family 2; PFAM: Protein of unknown function DUF2284, metal-binding; Methyltransferase type 12.
       0.835
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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