STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB95429.1Magnesium chelatase family protein; InterPro IPR004482:IPR003593:IPR001208:IPR000523; COGs: COG0606 ATPase with chaperone activity; KEGG: mta:Moth_1022 Mg chelatase-related protein; SMART: AAA ATPase; PFAM: magnesium chelatase ChlI subunit; TIGRFAM: Mg chelatase, subunit ChlI; SPTR: Mg chelatase-related protein. (506 aa)    
Predicted Functional Partners:
SMB95451.1
DNA protecting protein DprA; InterPro IPR003488; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; KEGG: mta:Moth_1025 DNA processing protein DprA, putative; SPTR: DNA processing protein DprA, putative; PFAM: SMF family protein; TIGRFAM: DNA protecting protein DprA.
 
 0.964
SMB95397.1
Putative endonuclease; InterPro IPR003509; KEGG: mta:Moth_0988 hypothetical protein; SPTR: UPF0102 protein Moth_0988; PFAM: Uncharacterised protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase.
 
  
 0.854
SMB91443.1
comF family protein; InterPro IPR000836; COGs: COG1040 amidophosphoribosyltransferase; KEGG: mta:Moth_0225 phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: phosphoribosyltransferase.
 
  
 0.833
SMB92897.1
Competence protein ComEC; InterPro IPR004477:IPR004797; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2; SPTR: DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein.
 
  
 0.746
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      0.728
SMB95424.1
Ribonuclease J; InterPro IPR011108; COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; KEGG: dau:Daud_0808 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase.
     
 0.637
SMB91214.1
Protoporphyrin IX magnesium-chelatase; InterPro IPR003593:IPR000523; COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: dau:Daud_1208 magnesium chelatase; SPTR: Magnesium chelatase; SMART: AAA ATPase; PFAM: magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase.
     
 0.608
tsf
Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
      0.584
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.575
murJ-2
Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.572
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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