STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnc-2RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (250 aa)    
Predicted Functional Partners:
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.898
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.891
rpmA
LSU ribosomal protein L27P; InterPro IPR001684:IPR018261; COGs: COG0211 Ribosomal protein L27; KEGG: tte:TTE0915 50S ribosomal protein L27; SPTR: 50S ribosomal protein L27; PFAM: ribosomal protein L27; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.879
rpsI
SSU ribosomal protein S9P; InterPro IPR020574:IPR000754; COGs: COG0103 Ribosomal protein S9; KEGG: mta:Moth_2424 SSU ribosomal protein S9P; SPTR: 30S ribosomal protein S9; PFAM: ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.875
rpmF
InterPro IPR002677; COGs: COG0333 Ribosomal protein L32; KEGG: ribosomal protein L32; SPTR: 50S ribosomal protein L32; PFAM: ribosomal L32p protein; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.874
rpsB
SSU ribosomal protein S2P; InterPro IPR018130:IPR005706:IPR001865; COGs: COG0052 Ribosomal protein S2; KEGG: mta:Moth_1032 SSU ribosomal protein S2P; SPTR: 30S ribosomal protein S2; PFAM: ribosomal protein S2; TIGRFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.871
SMB97202.1
Hypothetical protein; InterPro IPR004013:IPR003141; COGs: COG0613 metal-dependent phosphoesterase (PHP family); KEGG: mta:Moth_1085 PHP-like; SPTR: PHP-like; SMART: phosphoesterase PHP domain protein; PFAM: PHP domain protein.
    
 0.870
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.867
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.866
rpsP
SSU ribosomal protein S16P; InterPro IPR000307:IPR020592; COGs: COG0228 Ribosomal protein S16; KEGG: mta:Moth_0967 SSU ribosomal protein S16P; PFAM: ribosomal protein S16; TIGRFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.866
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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