STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB97131.1Repressor LexA; InterPro IPR006197:IPR019759; COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); KEGG: dae:Dtox_0891 peptidase S24 and S26 domain protein; SPTR: Peptidase S24 and S26 domain protein; PFAM: Peptidase S24/S26A/S26B, conserved region. (210 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.960
recA-2
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.958
SMB97126.1
Hypothetical protein; KEGG: ddr:Deide_14230 putative polyprenyl synthetase; SPTR: Putative Polyprenyl synthetase.
  
 
 0.839
SMB97135.1
Uncharacterized conserved protein YecE, DUF72 family; InterPro IPR002763; COGs: COG1801 conserved hypothetical protein; KEGG: mta:Moth_0268 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein.
       0.759
SMB98550.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.714
dinG
ATP-dependent DNA helicase DinG; 3'-5' exonuclease.
  
  
 0.637
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
  
   
 0.528
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
   
 0.517
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
  
   
 0.482
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.472
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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