STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (516 aa)    
Predicted Functional Partners:
SMB97334.1
Cobalt-precorrin 3 C17-methyltransferase; InterPro IPR006363:IPR000878; COGs: COG1010 Precorrin-3B methylase; KEGG: mta:Moth_1094 precorrin-3 methyltransferase; SPTR: Precorrin-3 methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase.
  
 0.999
SMB97342.1
precorrin-8X methylmutase; InterPro IPR003722; COGs: COG2082 Precorrin isomerase; KEGG: mta:Moth_1097 precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase.
  
 0.999
SMB97306.1
Adenosylcobinamide kinase; InterPro IPR003203; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; KEGG: dae:Dtox_3094 adenosylcobinamide-phosphateguanylyltransferase; SPTR:Adenosylcobinamide-phosphateguanylyltransferas e; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase.
 
 0.998
SMB97323.1
COGs: COG2243 Precorrin-2 methylase; KEGG: mta:Moth_1091 cobalt-factor II C20-methyltransferase.
 
  
 0.998
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.998
SMB97316.1
cobalt-precorrin-6B (C15)-methyltransferase; InterPro IPR014008:IPR000241; COGs: COG2242 Precorrin-6B methylase 2; KEGG: mta:Moth_1090 SAM (and some other nucleotide) binding protein; SPTR: SAM (And some other nucleotide) binding protein; PFAM: RNA methylase; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; manually curated.
 
  
 0.997
SMB97326.1
Cobalt-precorrin 4 C11-methyltransferase; InterPro IPR003043:IPR006362:IPR000878; COGs: COG2875 Precorrin-4 methylase; KEGG: mta:Moth_1092 precorrin-4 C11-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.997
SMB97357.1
L-threonine O-3-phosphate decarboxylase; InterPro IPR004838:IPR005860:IPR004839; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; KEGG: mta:Moth_1104 L-threonine O-3-phosphate decarboxylase; SPTR: L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; manually curated.
 
 0.991
cbiA
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.990
SMB97337.1
InterPro IPR003723; COGs: COG2099 Precorrin-6x reductase; KEGG: mta:Moth_1095 precorrin-6A reductase; SPTR: Precorrin-6A reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase.
 
  
 0.987
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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