STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB97482.1InterPro IPR006158:IPR006159; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); KEGG: tte:TTE2388 methylmalonyl-CoA mutase C-terminal domain-containing protein; SPTR: Methylmalonyl-CoA mutase, C-terminal domain/subunit (Cobalamin-binding); PFAM: cobalamin B12-binding domain protein. (139 aa)    
Predicted Functional Partners:
SMB97480.1
methylmalonyl-CoA mutase; InterPro IPR006099:IPR006098; COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; KEGG: tpd:Teth39_0902 methylmalonyl-CoA mutase, large subunit; SPTR: Methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit.
 0.999
SMB97488.1
methylmalonyl-CoA epimerase; InterPro IPR004360:IPR017515; COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; KEGG: tpd:Teth39_0905 glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; TIGRFAM: methylmalonyl-CoA epimerase.
  
 0.999
SMB97485.1
LAO/AO transport system kinase; InterPro IPR005129; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; KEGG: pfu:PF1947 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase.
  
 0.991
SMB97474.1
succinyl-CoA:acetate CoA-transferase; InterPro IPR003702:IPR017821; COGs: COG0427 Acetyl-CoA hydrolase; KEGG: vpr:Vpar_1249 succinate CoA transferase; SPTR: Acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase.
  
 
 0.931
SMB89163.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterProIPR011895:IPR017896:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_0064 pyruvate:ferredoxin (flavodoxin) oxidoreductase; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing p [...]
    
 0.919
SMB98582.1
Oxaloacetate decarboxylase, alpha subunit; InterProIPR001249:IPR000891:IPR003379:IPR000089:IPR 001882; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: mta:Moth_1525 pyruvate carboxylase subunit B; SPTR: Acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein.
    
 0.877
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.866
SMB93726.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; InterPro IPR002880; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_1984 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
     
 0.851
SMB99181.1
Acyl-CoA hydrolase; InterPro IPR003702; COGs: COG0427 Acetyl-CoA hydrolase; KEGG: tte:TTE0554 acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase.
  
 
 0.795
SMB99232.1
Acyl-CoA hydrolase; InterPro IPR003702; COGs: COG0427 Acetyl-CoA hydrolase; KEGG: tte:TTE0554 acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase.
  
 
 0.795
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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