STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pheAPrephenate dehydratase; InterPro IPR001086:IPR002912:IPR018528; COGs: COG0077 Prephenate dehydratase; KEGG: mta:Moth_1334 prephenate dehydratase; SPTR: Prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase. (287 aa)    
Predicted Functional Partners:
SMB98332.1
Prephenate dehydrogenase; InterPro IPR003099:IPR002912; COGs: COG0287 Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydrogenase.
 
 0.991
SMB98336.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; InterPro IPR006268:IPR006218; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; KEGG: mta:Moth_1335 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
 
 0.990
SMB98081.1
Aminotransferase; InterPro IPR001176:IPR004839:IPR004838; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; KEGG: mta:Moth_1188 aminotransferase; SPTR: Aminotransferase; PFAM: aminotransferase class I and II.
 
 
 0.961
SMC00140.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; InterPro IPR006218:IPR006268; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; KEGG: mta:Moth_2412 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; SPTR: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
 
 0.959
SMB98354.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
    
 0.955
SMB99239.1
Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
      0.931
SMB93661.1
Aminotransferase; InterPro IPR004839:IPR004838:IPR001176; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; KEGG: jan:Jann_4126 aromatic amino acid aminotransferase; SPTR: Aromatic amino acid aminotransferase; PFAM: aminotransferase class I and II.
 
 
 0.913
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.894
hisC
InterPro IPR005861:IPR004839:IPR001176; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; KEGG: mta:Moth_0515 histidinol phosphate aminotransferase; SPTR: Histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.891
SMB98477.1
L-aspartate aminotransferase apoenzyme; InterPro IPR004839:IPR004838:IPR001176; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; KEGG: mta:Moth_1490 L-aspartate aminotransferase; SPTR: L-aspartate aminotransferase; PFAM: aminotransferase class I and II.
 
 
 0.890
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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