STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (282 aa)    
Predicted Functional Partners:
SMB98550.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
 0.972
SMB99676.1
Myo-inositol-1(or 4)-monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; KEGG: inositol monophosphatase; SPTR: Inositol monophosphatase; InterPro IPR020550:IPR000760; PFAM: inositol monophosphatase.
 
 
  0.952
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
 
  
 0.938
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.932
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.903
SMB98558.1
23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase; InterPro IPR004538:IPR002942:IPR002877; COGs: COG1189 rRNA methylase; KEGG: mta:Moth_1510 hemolysin A; SPTR: Hemolysin A; SMART: RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; TIGRFAM: hemolysin A.
  
  
 0.891
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.888
SMB91750.1
InterPro IPR003000; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; KEGG: pth:PTH_2664 NAD-dependent protein deacetylases; SPTR: NAD-dependent protein deacetylases; PFAM: Silent information regulator protein Sir2.
  
 
 0.887
SMB98546.1
ADP-ribose pyrophosphatase; InterPro IPR000086:IPR020084; KEGG: mta:Moth_1504 NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX hydrolase.
    
 0.781
SMB92854.1
Metal dependent phosphohydrolase; InterPro IPR003607:IPR006674:IPR005249; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; KEGG: mta:Moth_0566 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region; PFAM: metal-dependent phosphohydrolase HD sub domain.
     
 0.708
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.