STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB98837.1DNA-binding transcriptional regulator, FrmR family; InterPro IPR003735; COGs: COG1937 conserved hypothetical protein; KEGG: mta:Moth_1674 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function DUF156. (90 aa)    
Predicted Functional Partners:
SMB89013.1
Copper chaperone; InterPro IPR006121:IPR001802:IPR017969; COGs: COG2608 Copper chaperone; KEGG: chy:CHY_0939 heavy metal-binding domain-containing protein; SPTR: Heavy-metal-associated domain protein; PFAM: Heavy metal transport/detoxification protein.
  
  
 0.848
SMB99887.1
Cu+-exporting ATPase; InterProIPR018303:IPR017969:IPR006121:IPR008250:IPR 005834:IPR001757:IPR001877:IPR001756:IPR006122:IPR006403:I PR006416; COGs: COG2217 Cation transport ATPase; KEGG: mta:Moth_1994 heavy metal translocating P-type ATPase; SPTR: Heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding protein; ATPase, P-type (transporting), HAD superfamily, [...]
 
  
 0.629
SMB94031.1
InterPro IPR001543:IPR001172; COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; KEGG: mta:Moth_0784 flagellar motor switch FliN; SPTR: Flagellar motor switch FliN; PFAM: surface presentation of antigens (SPOA) protein.
    
   0.609
SMB94150.1
Flagellar motor switch protein FliN/FliY; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; KEGG: mta:Moth_0805 flagellar motor switch protein; SPTR: CheC, inhibitor of MCP methylation; InterPro IPR012826:IPR007597:IPR001543:IPR001172; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; TIGRFAM: flagellar motor switch protein FliN.
    
   0.609
SMB96597.1
InterPro IPR001172:IPR001543; COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; KEGG: CheC, inhibitor of MCP methylation / FliN fusion protein; SPTR: Flagellar motor switch protein FliY; PFAM: surface presentation of antigens (SPOA) protein.
    
   0.609
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.582
sigI
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.
   
   0.545
hisS
histidyl-tRNA synthetase; InterProIPR006195:IPR015807:IPR004516:IPR002314:IPR 004154; COGs: COG0124 Histidyl-tRNA synthetase; KEGG: mta:Moth_1677 histidyl-tRNA synthetase; SPTR: Histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; TIGRFAM: histidyl-tRNA synthetase.
       0.529
SMB99403.1
Cd2+/Zn2+-exporting ATPase; InterProIPR018303:IPR008250:IPR005834:IPR006404:IPR 006416:IPR001757:IPR001366; COGs: COG2217 Cation transport ATPase; KEGG: mta:Moth_2203 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; SPTR: Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; TIGRFAM: cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.
 
  
 0.512
SMB98843.1
Glyoxylase, beta-lactamase superfamily II; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: mta:Moth_1678 beta-lactamase-like; SPTR: Beta-lactamase-like.
     
 0.497
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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