STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB99217.1PAS domain S-box-containing protein; InterProIPR002078:IPR000014:IPR003593:IPR013767:IPR 002197:IPR020441; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; KEGG: ctc:CTC00707 transcriptional regulatory protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; SMART: AAA ATPase; PAS domain containing protein; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold domain protein; helix-turn-helix Fis-type; TIGRFAM: PAS sensor protein. (578 aa)    
Predicted Functional Partners:
SMB91526.1
RNA polymerase, sigma 54 subunit, RpoN/SigL; InterPro IPR000394:IPR007046:IPR007634; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; KEGG: mta:Moth_0261 sigma-54 (RpoN); SPTR: Sigma-54 (RpoN); PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN.
 
  
 0.832
SMB98646.1
Two-component system, cell cycle response regulator DivK; InterPro IPR001789; COGs: COG0784 FOG: CheY-like receiver; KEGG: mma:MM_1068 two-component response regulator; SPTR: Response regulator receiver protein; SMART: response regulator receiver; PFAM: response regulator receiver.
    
 0.561
SMB99324.1
Signal transduction histidine kinase; InterProIPR017204:IPR003660:IPR003594:IPR011712:IPR 005467:IPR004358; COGs: COG4585 Signal transduction histidine kinase; KEGG: dhd:Dhaf_1193 histidine kinase; SPTR: Sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein.
     
 0.506
SMB97683.1
Hypothetical protein; InterPro IPR004358:IPR003661:IPR003594:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: mta:Moth_1138 histidine kinase; SPTR: Sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
   
 0.481
SMB89650.1
COGs: COG0642 Signal transduction histidine kinase; KEGG: lch:Lcho_0047 histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; SPTR: Sensor protein; InterProIPR005467:IPR004358:IPR003661:IPR003594:IPR 007891.
     
 0.456
SMB98649.1
InterPro IPR001789; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: cag:Cagg_0863 response regulator receiver modulated metal dependent phosphohydrolase; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; SMART: response regulator receiver; PFAM: response regulator receiver.
    
 0.452
SMB99729.1
Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004090; COGs: COG0840 Methyl-accepting chemotaxis protein; KEGG: bay:RBAM_028310 TlpA; SPTR: Methyl-accepting chemotaxis protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
     
 0.452
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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