STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)    
Predicted Functional Partners:
SMB98579.1
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 0.999
SMB98582.1
Oxaloacetate decarboxylase, alpha subunit; InterProIPR001249:IPR000891:IPR003379:IPR000089:IPR 001882; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: mta:Moth_1525 pyruvate carboxylase subunit B; SPTR: Acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein.
 
 0.999
accA
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 0.999
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.994
SMB94811.1
[Acyl-carrier-protein] S-malonyltransferase; InterPro IPR004410:IPR014043; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; KEGG: mta:Moth_0947 [acyl-carrier-protein] S-malonyltransferase; SPTR: [Acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.994
SMB94827.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.989
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.970
SMB99183.1
3-oxoacyl-[acyl-carrier-protein] synthase-3; InterPro IPR013751:IPR013747; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); KEGG: nth:Nther_2744 hypothetical protein; SPTR: 3-oxoacyl-(Acyl carrier protein) synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III.
  
 
 0.948
SMB99231.1
3-oxoacyl-[acyl-carrier-protein] synthase-3; InterPro IPR013751:IPR013747; KEGG: tte:TTE0553 hypothetical protein; SPTR: 3-Oxoacyl-(Acyl-carrier-protein) synthase III C terminal domain protein; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III.
  
 
 0.948
SMB92225.1
Propionate CoA-transferase; InterPro IPR004165:IPR014388; COGs: COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; KEGG: mta:Moth_1259 propionate CoA-transferase; SPTR: Propionate CoA-transferase; PFAM: coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family.
  
 0.914
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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