STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFI00645.1CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (167 aa)    
Predicted Functional Partners:
cas1
CRISP-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 
 0.993
SFI00670.1
CRISPR-associated helicase Cas3.
 
  
 0.954
SFI00702.1
CRISPR-associated protein, Cas5h family.
 
   
 0.932
SFI00729.1
CRISPR-associated protein, Csh2 family.
 
   
 0.921
SFI00774.1
CRISPR-associated protein, Cas6 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
   
 0.917
SFI00570.1
CRISPR-associated protein, Cmr2 family.
 
   
 0.647
SFI00497.1
CRISPR-associated protein, Cmr4 family.
 
     0.605
SFI00753.1
Hypothetical protein.
       0.499
SFI00547.1
CRISPR-associated protein, Cmr3 family.
 
     0.489
SFI00594.1
CRISPR-associated protein Cmr1.
 
     0.479
Your Current Organism:
Tindallia magadiensis
NCBI taxonomy Id: 69895
Other names: DSM 10318, T. magadiensis, Tindallia magadii, strain Z-7934
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.