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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCP88262.1Hypothetical protein, (similar to IcmE protein), partial CDS. (184 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B.
   
 
 0.874
topA
Topoisomerase IA, partial CDS; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removin [...]
     
 0.585
CCP88263.1
Conserved hypothetical protein, partial CDS.
       0.523
phnL
ABC transporter, ATPase component; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
     
 0.501
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
    0.467
dppA
ABC-type dipeptide-binding protein, solute binding protein.
     
 0.437
hlyC1
Hymolysin-related protein.
     
 0.425
Your Current Organism:
Phytoplasma solani
NCBI taxonomy Id: 69896
Other names: C. Phytoplasma solani, Candidatus Phytoplasma solani, Stolbur phytoplasma, strain STOL11
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