| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| lig | rpoB | S284_03270 | S284_04660 | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.405 |
| lig | whiA | S284_03270 | S284_03280 | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.707 |
| polC2 | polC3 | S284_00770 | S284_05130 | DNA polymerase III alpha subunit, partial CDS; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III alpha subunit, partial CDS. | 0.976 |
| polC2 | whiA | S284_00770 | S284_03280 | DNA polymerase III alpha subunit, partial CDS; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.586 |
| polC2 | yqeK | S284_00770 | S284_03410 | DNA polymerase III alpha subunit, partial CDS; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Predicted HD superfamily hydrolase. | 0.690 |
| polC3 | polC2 | S284_05130 | S284_00770 | DNA polymerase III alpha subunit, partial CDS. | DNA polymerase III alpha subunit, partial CDS; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.976 |
| polC3 | whiA | S284_05130 | S284_03280 | DNA polymerase III alpha subunit, partial CDS. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.584 |
| polC3 | yqeK | S284_05130 | S284_03410 | DNA polymerase III alpha subunit, partial CDS. | Predicted HD superfamily hydrolase. | 0.686 |
| pykF | rpoA | S284_00050 | S284_01640 | Pyruvate kinase; Belongs to the pyruvate kinase family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.629 |
| pykF | rpoB | S284_00050 | S284_04660 | Pyruvate kinase; Belongs to the pyruvate kinase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.670 |
| pykF | rpoC | S284_00050 | S284_04670 | Pyruvate kinase; Belongs to the pyruvate kinase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.692 |
| pykF | rpoD | S284_00050 | S284_01980 | Pyruvate kinase; Belongs to the pyruvate kinase family. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.445 |
| pykF | rpoZ | S284_00050 | S284_05060 | Pyruvate kinase; Belongs to the pyruvate kinase family. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.468 |
| pykF | whiA | S284_00050 | S284_03280 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.493 |
| rpoA | pykF | S284_01640 | S284_00050 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.629 |
| rpoA | rpoB | S284_01640 | S284_04660 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| rpoA | rpoC | S284_01640 | S284_04670 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| rpoA | rpoD | S284_01640 | S284_01980 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.951 |
| rpoA | rpoZ | S284_01640 | S284_05060 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.990 |
| rpoA | whiA | S284_01640 | S284_03280 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.784 |