Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
casCCRISPR system CASCADE complex protein CasC; Identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869. (361 aa)    
Predicted Functional Partners:
casD
CRISPR system CASCADE complex protein CasD; Identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593.
 
 
 0.997
casA
CRISPR system CASCADE complex protein CasA; Identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547.
 
 
 0.997
casB
CRISPR system CASCADE complex protein CasB; Identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548.
 
 
 0.996
casE
CRISPR system CASCADE complex protein CasE; Identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907.
 
 
 0.994
cas3
CRISPR-associated helicase Cas3; Identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587; match to protein family HMM TIGR01596.
 
 
 0.992
cas1
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.968
cas2
CRISPR-associated endoribonuclease Cas2; Identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873.
 
  
 0.965
EFD93807.1
Histidine triad domain protein; Identified by match to protein family HMM PF01230.
       0.410
yqeV
tRNA methylthiotransferase YqeV; Identified by match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579.
       0.410
EFD93809.1
RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.410
Your Current Organism:
Megasphaera genomosp.
NCBI taxonomy Id: 699218
Other names: M. genomosp. type_1 str. 28L, Megasphaera genomosp. type_1 str. 28L
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