Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFD93375.1Helicase C-terminal domain protein; Identified by match to protein family HMM PF00271. (2905 aa)    
Predicted Functional Partners:
EFD93612.1
Type I restriction modification DNA specificity domain protein; Identified by match to protein family HMM PF01420.
  
 0.935
EFD94732.1
Hypothetical protein; Identified by glimmer; putative.
  
 0.935
EFD93376.1
Single-strand binding family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00436.
 
     0.910
EFD93372.1
Hypothetical protein.
 
     0.872
EFD93369.1
Hypothetical protein.
 
     0.862
EFD93367.1
Hypothetical protein.
 
     0.843
EFD93368.1
Hypothetical protein.
 
     0.807
EFD93373.1
DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751.
 
     0.803
EFD93354.1
Identified by match to protein family HMM PF02534.
 
    0.789
EFD93355.1
Hypothetical protein.
 
     0.774
Your Current Organism:
Megasphaera genomosp.
NCBI taxonomy Id: 699218
Other names: M. genomosp. type_1 str. 28L, Megasphaera genomosp. type_1 str. 28L
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