Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mutYA/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)    
Predicted Functional Partners:
EFD93318.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
    
 0.848
EFD93319.1
Putative exodeoxyribonuclease III; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
    
 0.848
EFD93652.1
Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF00149.
       0.828
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.819
sfsA
Sugar fermentation stimulation protein; Identified by match to protein family HMM PF01986; match to protein family HMM PF03749; match to protein family HMM TIGR00230; Belongs to the SfsA family.
 
    0.720
EFD94280.1
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 
 0.649
EFD93650.1
Hypothetical protein.
       0.544
EFD93648.1
Hypothetical protein.
       0.532
EFD93649.1
Identified by match to protein family HMM PF00149.
       0.532
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
    
 0.517
Your Current Organism:
Megasphaera genomosp.
NCBI taxonomy Id: 699218
Other names: M. genomosp. type_1 str. 28L, Megasphaera genomosp. type_1 str. 28L
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