Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (451 aa)    
Predicted Functional Partners:
glmS
Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.971
dacA
TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.970
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
 
 0.969
EFD94777.1
Hypothetical protein; Identified by glimmer; putative.
     
 0.867
EFD94755.1
Hexokinase; Identified by match to protein family HMM PF00349; match to protein family HMM PF03727.
   
 
 0.865
EFD93746.1
Identified by match to protein family HMM PF07949.
  
  
 0.831
EFD93747.1
FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266.
       0.785
EFD94773.1
AMP-binding enzyme; Identified by match to protein family HMM PF00501.
    
 0.742
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
 
  
 0.654
EFD93500.1
Sugar isomerase, KpsF/GutQ family; Identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
   
 0.607
Your Current Organism:
Megasphaera genomosp.
NCBI taxonomy Id: 699218
Other names: M. genomosp. type_1 str. 28L, Megasphaera genomosp. type_1 str. 28L
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