STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC91642.1Fructose-1,6-bisphosphate aldolase; Identified by match to protein family HMM PF00274. (295 aa)    
Predicted Functional Partners:
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.971
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.951
ADC91224.1
Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF01113; match to protein family HMM PF02800; match to protein family HMM TIGR01546.
  
 0.950
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.923
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.922
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family.
   
 0.908
ADC90348.1
Transketolase, C-terminal domain protein; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
     
  0.900
ADC91380.1
Transketolase, thiamine diphosphate binding domain protein; Identified by match to protein family HMM PF00456.
     
  0.900
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
  0.900
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.885
Your Current Organism:
Mageeibacillus indolicus
NCBI taxonomy Id: 699246
Other names: Clostridiales genomosp. BVAB3 str. UPII9-5, M. indolicus UPII9-5, Mageeibacillus indolicus UPII9-5
Server load: low (18%) [HD]