STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (288 aa)    
Predicted Functional Partners:
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.
    
 0.910
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
     
 0.823
ADC91380.1
Transketolase, thiamine diphosphate binding domain protein; Identified by match to protein family HMM PF00456.
    
  0.807
ADC90348.1
Transketolase, C-terminal domain protein; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
    
  0.805
prs
Ribose-phosphate diphosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 
  0.803
prs-2
Ribose-phosphate diphosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 
  0.803
ADC91298.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879.
     
  0.800
ADC91751.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
     
  0.800
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
  0.800
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.799
Your Current Organism:
Mageeibacillus indolicus
NCBI taxonomy Id: 699246
Other names: Clostridiales genomosp. BVAB3 str. UPII9-5, M. indolicus UPII9-5, Mageeibacillus indolicus UPII9-5
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.