STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_00613COG4474 Uncharacterized protein conserved in bacteria; Belongs to the UPF0398 family. (173 aa)    
Predicted Functional Partners:
SRA_06386
TPR repeat-containing protein; COG0457 FOG: TPR repeat.
  
     0.748
SRA_00383
COG4473 Predicted ABC-type exoprotein transport system, permease component.
  
     0.726
recU
Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
  
 0.723
SRA_01527
Hypothetical protein; COG0827 Adenine-specific DNA methylase.
  
     0.694
SRA_00603
Penicillin-binding protein 1a; Membrane carboxypeptidase; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
     0.651
gpsB
Hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
   
 0.649
SRA_03771
Integral membrane protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.
  
     0.607
dinG
Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; 3'-5' exonuclease.
 
     0.527
SRA_03001
COG3091 Uncharacterized protein conserved in bacteria; Belongs to the SprT family.
  
     0.507
SRA_07531
COG4698 Uncharacterized protein conserved in bacteria.
  
     0.489
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.