STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ManACOG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (315 aa)    
Predicted Functional Partners:
SRA_00967
Fructokinase; COG1940 Transcriptional regulator/sugar kinase.
 
 
 0.968
ManX
Putative PTS system, mannose-specific component IIAB; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
 
  
 0.963
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.954
SRA_01122
COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
 
  
 0.943
SRA_01127
PTS system, mannose-specific IID component; COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID.
 
  
  0.937
mtlD
COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
 
  
 0.924
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.917
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.914
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.914
SRA_08436
COG0036 Pentose-5-phosphate-3-epimerase.
    
 0.912
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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