STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LepBCOG0681 Signal peptidase I; Belongs to the peptidase S26 family. (195 aa)    
Predicted Functional Partners:
LepB-2
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
  
  
 
0.920
rnhC
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.783
recD2
Putative exodeoxyribonuclease V, conjugation transfer protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
       0.615
SRA_01087
COG1286 Uncharacterized membrane protein, required for colicin V production.
  
    0.546
SRA_01092
Hypothetical protein.
       0.534
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.508
GltB
COG0067 Glutamate synthase domain 1.
     
 0.499
RseP
COG0750 Predicted membrane-associated Zn-dependent proteases 1.
 
  
 0.494
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.456
mutS2
Putative DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.441
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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