STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_01417COG0744 Membrane carboxypeptidase (penicillin-binding protein). (751 aa)    
Predicted Functional Partners:
SRA_00538
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.979
SRA_07486
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.956
gpsB
Hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.944
SRA_00603
Penicillin-binding protein 1a; Membrane carboxypeptidase; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
  
 
0.927
SRA_01597
COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
  
0.926
SRA_09698
COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.913
SRA_07431
Putative 40K cell wall protein precursor.
     
  0.900
SRA_03166
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
  
 
 
 0.775
SRA_03546
Putative cell division protein (cell shape determining protein); COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
  
 
 
 0.726
murF
Putative D-Ala-D-Ala adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.707
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.