| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SRA_00513 | scpA | SRA_00513 | SRA_02191 | Cell wall protein, WapE. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.838 |
| SRA_02171 | SRA_02176 | SRA_02171 | SRA_02176 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | COG0622 Predicted phosphoesterase. | 0.949 |
| SRA_02171 | SRA_02181 | SRA_02171 | SRA_02181 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; COG0517 FOG: CBS domain. | 0.800 |
| SRA_02171 | SRA_02201 | SRA_02171 | SRA_02201 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.800 |
| SRA_02171 | YidD | SRA_02171 | SRA_02206 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.800 |
| SRA_02171 | murI | SRA_02171 | SRA_02166 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.979 |
| SRA_02171 | scpA | SRA_02171 | SRA_02191 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.822 |
| SRA_02171 | scpB | SRA_02171 | SRA_02196 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.817 |
| SRA_02171 | xerD | SRA_02171 | SRA_02186 | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Site-specific tyrosine recombinase XerD-like protein; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily. | 0.801 |
| SRA_02176 | SRA_02171 | SRA_02176 | SRA_02171 | COG0622 Predicted phosphoesterase. | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.949 |
| SRA_02176 | SRA_02181 | SRA_02176 | SRA_02181 | COG0622 Predicted phosphoesterase. | Hypothetical protein; COG0517 FOG: CBS domain. | 0.850 |
| SRA_02176 | SRA_02201 | SRA_02176 | SRA_02201 | COG0622 Predicted phosphoesterase. | Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.806 |
| SRA_02176 | YidD | SRA_02176 | SRA_02206 | COG0622 Predicted phosphoesterase. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.800 |
| SRA_02176 | murI | SRA_02176 | SRA_02166 | COG0622 Predicted phosphoesterase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| SRA_02176 | scpA | SRA_02176 | SRA_02191 | COG0622 Predicted phosphoesterase. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.800 |
| SRA_02176 | scpB | SRA_02176 | SRA_02196 | COG0622 Predicted phosphoesterase. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.806 |
| SRA_02176 | xerD | SRA_02176 | SRA_02186 | COG0622 Predicted phosphoesterase. | Site-specific tyrosine recombinase XerD-like protein; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily. | 0.800 |
| SRA_02181 | SRA_02171 | SRA_02181 | SRA_02171 | Hypothetical protein; COG0517 FOG: CBS domain. | Putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.800 |
| SRA_02181 | SRA_02176 | SRA_02181 | SRA_02176 | Hypothetical protein; COG0517 FOG: CBS domain. | COG0622 Predicted phosphoesterase. | 0.850 |
| SRA_02181 | SRA_02201 | SRA_02181 | SRA_02201 | Hypothetical protein; COG0517 FOG: CBS domain. | Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.800 |