STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PflAPyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (263 aa)    
Predicted Functional Partners:
PflB
COG1882 Pyruvate-formate lyase.
  
 0.965
AdhE
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.763
SRA_04241
PduQ protein, putative; COG1454 Alcohol dehydrogenase, class IV.
 
  
 0.532
ppaC
COG1227 Inorganic pyrophosphatase/exopolyphosphatase.
       0.506
SRA_02291
COG1253 Hemolysins and related proteins containing CBS domains.
  
    0.481
SRA_03236
COG1454 Alcohol dehydrogenase, class IV.
  
  
 0.440
SRA_07101
Hypothetical protein; COG1866 Phosphoenolpyruvate carboxykinase (ATP).
   
  
 0.437
SRA_06241
COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
   
  
 0.403
SRA_10273
COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
   
  
 0.403
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.