STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_03236COG1454 Alcohol dehydrogenase, class IV. (385 aa)    
Predicted Functional Partners:
SRA_04286
Acetaldehyde dehydrogenase (acetylating); COG1012 NAD-dependent aldehyde dehydrogenases.
 
 0.972
SRA_03231
COG3395 Uncharacterized protein conserved in bacteria.
 
     0.863
PdxA
4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.
 
     0.803
SRA_03226
COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains.
 
   
 0.752
SRA_03251
Hypothetical protein; COG4692 Predicted neuraminidase (sialidase).
 
     0.610
SRA_03246
Hypothetical protein.
       0.478
PflA
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
  
 0.440
AdhE
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
0.435
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.431
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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