STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsEPutative ABC transporter, ATP-binding component; Part of the ABC transporter FtsEX involved in cellular division. (230 aa)    
Predicted Functional Partners:
SRA_03296
Putative cell-division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 0.995
SRA_04381
ABC transporter, permease protein, putative; COG0577 ABC-type antimicrobial peptide transport system, permease component.
   
 0.845
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
  
    0.644
SRA_02004
Putative secreted antigen GbpB/SagA; Putative peptidoglycan hydrolase; COG3883 Uncharacterized protein conserved in bacteria.
 
  
 0.554
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.484
SRA_03746
Hypothetical protein.
  
  
 0.479
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.479
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.449
SRA_07656
COG3599 Cell division initiation protein.
  
  
 0.417
QueG
Iron-sulfur cluster-binding protein; COG1600 Uncharacterized Fe-S protein.
       0.409
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.