Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SRA_03301Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (210 aa)    
Predicted Functional Partners:
GloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.956
SRA_02506
COG0346 Lactoylglutathione lyase and related lyases.
  
 0.911
SRA_05356
Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
  
 0.911
SRA_08726
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
 0.755
SRA_03311
Hypothetical protein; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
       0.608
SRA_03306
Acetoin reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
   
 
 0.569
CysE
COG1045 Serine acetyltransferase.
      
 0.561
SRA_05416
NADH oxidase (H2O-forming); COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
 0.544
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
 
   
 0.539
SRA_03316
COG4947 Uncharacterized protein conserved in bacteria.
       0.514
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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