STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_03306Acetoin reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (254 aa)    
Predicted Functional Partners:
BudA
COG3527 Alpha-acetolactate decarboxylase.
  
  
 0.927
FabD
COG0331 (acyl-carrier-protein) S-malonyltransferase.
 
 0.597
SRA_03301
Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases.
  
 
 0.587
SRA_03311
Hypothetical protein; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
  
 
 0.532
SRA_02591
Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.531
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.460
FabF
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.455
SRA_08331
COG4578 Glucitol operon activator.
  
  
 0.453
srlA
PTS system, sorbitol (glucitol) phosphotransferase enzyme IIC2; COG3730 Phosphotransferase system sorbitol-specific component IIC.
  
    0.443
SRA_05861
Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.
  
  
 0.440
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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