STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_03436Malate dehydrogenase; COG0281 Malic enzyme. (540 aa)    
Predicted Functional Partners:
SRA_03441
COG0679 Predicted permeases.
 
  
 0.936
SRA_07136
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.869
SRA_09251
Hypothetical protein; COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes.
 
  
 0.836
LpdA-2
COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
  
 0.622
SRA_04491
COG0679 Predicted permeases.
  
  
 0.574
SRA_10063
Putative oxidoreductase; Fumarate reductase; COG0431 Predicted flavoprotein.
  
  
 0.567
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.541
GltB
COG0067 Glutamate synthase domain 1.
     
 0.537
SRA_03431
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
 
 
 0.532
SRA_09256
Putative glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
  
 0.484
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.