STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_03891Hypothetical protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (226 aa)    
Predicted Functional Partners:
SRA_03896
COG0642 Signal transduction histidine kinase.
 
 
 0.972
SRA_01567
COG0642 Signal transduction histidine kinase.
 
 0.860
SRA_10113
COG0642 Signal transduction histidine kinase.
 
 
 0.831
SRA_05471
Putative histidine kinase sensor CiaH; COG0642 Signal transduction histidine kinase.
 
 
 0.829
VicK
Putative histidine kinase CovS; VicK-like protein; COG5002 Signal transduction histidine kinase.
 
 0.801
SRA_04601
COG0642 Signal transduction histidine kinase.
 
 
 0.784
SRA_05106
COG0642 Signal transduction histidine kinase.
 
 
 0.764
SRA_07226
COG0642 Signal transduction histidine kinase.
 
 
 0.685
SRA_05561
Hypothetical protein; COG0642 Signal transduction histidine kinase.
 
 
 0.594
dltA
D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
  
  
 0.558
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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