STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_04191Cell surface protein precursor. (924 aa)    
Predicted Functional Partners:
SRA_03126
COG2035 Predicted membrane protein.
  
     0.686
SRA_06296
Putative endoglucanase precursor; COG3405 Endoglucanase Y; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
     0.631
SRA_05191
Cell wall-associated protein precursor WapA; COG4932 Predicted outer membrane protein.
  
     0.575
SRA_06301
COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
 
   
 0.524
gtfA
Glycosyltransferase, putative teichoic acid biosynthesis protein; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
 
     0.518
gtfB
Hypothetical protein; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
 
     0.505
SRA_04831
Putative deacetylase; COG0726 Predicted xylanase/chitin deacetylase.
  
   
 0.501
SRA_02966
Hypothetical protein.
  
     0.461
SRA_08996
Collagen-binding A precursor protein-like protein; COG4932 Predicted outer membrane protein.
 
   
 0.451
Asp3
Hypothetical protein.
 
     0.446
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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