Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SRA_04446Hypothetical protein. (173 aa)    
Predicted Functional Partners:
SRA_04451
COG4835 Uncharacterized protein conserved in bacteria.
       0.744
SRA_04456
DegV family protein; COG1307 Uncharacterized protein conserved in bacteria.
       0.744
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
       0.736
cca
tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
       0.736
SRA_04471
Putative ABC transporter, ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.
       0.736
SRA_04476
COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.575
SRA_04481
Putative ABC transporter, ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.
       0.554
SRA_04486
Putative ABC transporter, ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.
       0.551
SRA_04441
Hypothetical protein; COG0671 Membrane-associated phospholipid phosphatase.
       0.462
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
    0.404
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
Server load: low (30%) [HD]