STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MvaDCOG3407 Mevalonate pyrophosphate decarboxylase. (310 aa)    
Predicted Functional Partners:
SRA_04671
COG1577 Mevalonate kinase.
 
 
 0.998
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.995
SRA_07561
Putative farnesyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.939
Mvk
COG1577 Mevalonate kinase.
 
  
 0.925
SRA_04696
COG3425 3-hydroxy-3-methylglutaryl CoA synthase.
 
 
 0.905
SRA_04691
COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.852
SRA_05381
Oxidative damage repair enzyme; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
  
 0.561
lysS
COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.525
SRA_04646
Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.504
SRA_04651
Hypothetical protein.
       0.504
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.