| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FolB | FolK | SRA_04866 | SRA_04871 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.999 |
| FolB | FolP | SRA_04866 | SRA_04861 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| FolB | RarD | SRA_04866 | SRA_04846 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | rarD protein; COG2962 Predicted permeases. | 0.566 |
| FolB | SRA_04831 | SRA_04866 | SRA_04831 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative deacetylase; COG0726 Predicted xylanase/chitin deacetylase. | 0.447 |
| FolB | SRA_04836 | SRA_04866 | SRA_04836 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COG0460 Homoserine dehydrogenase. | 0.578 |
| FolB | SRA_04851 | SRA_04866 | SRA_04851 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative folyl-polyglutamate synthetase; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.827 |
| FolB | folE | SRA_04866 | SRA_04856 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COG0302 GTP cyclohydrolase I. | 0.983 |
| FolB | thrB | SRA_04866 | SRA_04841 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.566 |
| FolK | FolB | SRA_04871 | SRA_04866 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| FolK | FolP | SRA_04871 | SRA_04861 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| FolK | RarD | SRA_04871 | SRA_04846 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | rarD protein; COG2962 Predicted permeases. | 0.566 |
| FolK | SRA_04831 | SRA_04871 | SRA_04831 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Putative deacetylase; COG0726 Predicted xylanase/chitin deacetylase. | 0.447 |
| FolK | SRA_04836 | SRA_04871 | SRA_04836 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | COG0460 Homoserine dehydrogenase. | 0.573 |
| FolK | SRA_04851 | SRA_04871 | SRA_04851 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Putative folyl-polyglutamate synthetase; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.856 |
| FolK | folE | SRA_04871 | SRA_04856 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | COG0302 GTP cyclohydrolase I. | 0.998 |
| FolK | thrB | SRA_04871 | SRA_04841 | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.566 |
| FolP | FolB | SRA_04861 | SRA_04866 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| FolP | FolK | SRA_04861 | SRA_04871 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.999 |
| FolP | RarD | SRA_04861 | SRA_04846 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | rarD protein; COG2962 Predicted permeases. | 0.566 |
| FolP | SRA_04831 | SRA_04861 | SRA_04831 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Putative deacetylase; COG0726 Predicted xylanase/chitin deacetylase. | 0.447 |