STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_05116Putative ABC transporter, permease protein; COG0577 ABC-type antimicrobial peptide transport system, permease component. (672 aa)    
Predicted Functional Partners:
SRA_05121
Putative ABC transporter, ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
 
 0.978
SRA_05106
COG0642 Signal transduction histidine kinase.
 
 
 
 0.930
SRA_05111
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
     0.899
SRA_04371
Putative permease; COG0845 Membrane-fusion protein.
  
 
 0.723
SRA_06201
Putative ABC transporter, membrane protein subunit and ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
 
 0.723
SRA_08521
Putative ComB, accessory factor for ComA; COG0845 Membrane-fusion protein.
 
  
 0.599
SRA_05126
glucosyltransferase-I; COG0366 Glycosidases.
 
     0.579
SRA_09601
Hypothetical protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).
  
    0.515
SRA_05311
Putative ABC transporter, ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
  
 
 0.500
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.474
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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