STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_05206Putative transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (297 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.612
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.561
SRA_05146
COG0110 Acetyltransferase (isoleucine patch superfamily).
  
  
 0.549
SRA_02951
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
  
 0.519
SRA_05201
Hypothetical protein; COG3942 Surface antigen.
     
 0.502
AdhE
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.455
SRA_03471
Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
  
 
 0.430
SRA_03476
Putative acetate kinase; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
  
 
 0.430
SRA_04801
Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
  
 
 0.430
SRA_01784
Putative cation efflux pump (multidrug resistance protein); COG0534 Na+-driven multidrug efflux pump.
 
   
 0.412
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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