STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_05541COG4476 Uncharacterized protein conserved in bacteria; Belongs to the UPF0223 family. (92 aa)    
Predicted Functional Partners:
SRA_05536
Hypothetical protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
 
  
 0.880
spxA
Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
    0.809
SRA_05531
Methylase; COG0144 tRNA and rRNA cytosine-C5-methylases.
       0.688
SRA_05551
Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.
       0.637
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.596
SRA_08901
16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
     0.523
PstS
Putative ABC transporter, phosphate-binding protein; COG0226 ABC-type phosphate transport system, periplasmic component.
       0.502
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.497
SRA_07911
Hypothetical protein; COG5503 Uncharacterized conserved small protein; Belongs to the UPF0356 family.
 
   
 0.497
SRA_02161
COG3763 Uncharacterized protein conserved in bacteria.
  
     0.489
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.