STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtlDCOG0246 Mannitol-1-phosphate/altronate dehydrogenases. (378 aa)    
Predicted Functional Partners:
SRA_05711
PTS system, mannitol-specific enzyme IIA; COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain.
 
 0.999
SRA_05721
COG2213 Phosphotransferase system, mannitol-specific IIBC component.
 
 
 0.998
SRA_05716
Putative transcriptional regulator MtlR; COG3711 Transcriptional antiterminator.
 
  
 0.965
ManA
COG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
  
 0.924
SRA_08341
Sorbitol-6-phosphate 2-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.921
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.916
fbp
Fructose-1,6-bisphosphatase class 3; COG3855 Uncharacterized protein conserved in bacteria.
     
 0.910
SRA_00967
Fructokinase; COG1940 Transcriptional regulator/sugar kinase.
  
 
 0.908
SRA_08436
COG0036 Pentose-5-phosphate-3-epimerase.
    
 0.907
SRA_03636
COG3711 Transcriptional antiterminator.
 
  
 0.875
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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