STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)    
Predicted Functional Partners:
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.980
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.961
Pyk
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.956
SRA_09918
COG0191 Fructose/tagatose bisphosphate aldolase.
 
 
 0.940
Tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.929
SRA_00168
COG0191 Fructose/tagatose bisphosphate aldolase.
  
 
 0.923
SRA_03656
Hypothetical protein; COG0191 Fructose/tagatose bisphosphate aldolase.
  
 
 0.923
fbp
Fructose-1,6-bisphosphatase class 3; COG3855 Uncharacterized protein conserved in bacteria.
     
 0.917
mtlD
COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
    
 0.916
ManA
COG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.914
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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