STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_06451Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase. (236 aa)    
Predicted Functional Partners:
SRA_06446
Hypothetical protein.
  
 0.964
SRA_06456
DNA replication protein DnaD; COG3935 Putative primosome component and related proteins.
 
     0.841
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
       0.800
SRA_04936
Putative DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.755
SRA_09056
COG4472 Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.
  
     0.709
addA
Putative exonuclease RexA; ATP-dependent DNA helicase.
 
     0.653
SRA_06441
Putative oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating).
       0.650
SRA_00413
Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.
  
   
 0.635
whiA
Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.
  
     0.623
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.572
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.