STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacD-2COG3684 Tagatose-1,6-bisphosphate aldolase; Belongs to the aldolase LacD family. (326 aa)    
Predicted Functional Partners:
lacC
COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.992
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.905
lacD
COG3684 Tagatose-1,6-bisphosphate aldolase; Belongs to the aldolase LacD family.
  
  
 
0.901
lacB
Galactose-6-phosphate isomerase subunit LacB; COG0698 Ribose 5-phosphate isomerase RpiB.
 
  
 0.887
lacA
Galactose-6-phosphate isomerase subunit LacA; COG0698 Ribose 5-phosphate isomerase RpiB.
 
  
 0.867
SRA_07106
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 
  0.818
SRA_06561
PTS system, lactose-specific enzyme IIBC EIIBC-LAC; COG1455 Phosphotransferase system cellobiose-specific component IIC.
 
  
 0.810
SRA_06581
PTS system, IIB component, putative; COG3414 Phosphotransferase system, galactitol-specific IIB component.
 
     0.810
SRA_09668
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
     
  0.800
SRA_06576
PTS system, IIC component; COG3775 Phosphotransferase system, galactitol-specific IIC component.
 
     0.749
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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