STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacBGalactose-6-phosphate isomerase subunit LacB; COG0698 Ribose 5-phosphate isomerase RpiB. (171 aa)    
Predicted Functional Partners:
lacA
Galactose-6-phosphate isomerase subunit LacA; COG0698 Ribose 5-phosphate isomerase RpiB.
 
0.997
lacC
COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.988
lacG
6-phospho-beta-galactosidase; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.957
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.914
lacD-2
COG3684 Tagatose-1,6-bisphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.887
SRA_06581
PTS system, IIB component, putative; COG3414 Phosphotransferase system, galactitol-specific IIB component.
 
     0.813
SRA_06561
PTS system, lactose-specific enzyme IIBC EIIBC-LAC; COG1455 Phosphotransferase system cellobiose-specific component IIC.
 
  
 0.789
SRA_06576
PTS system, IIC component; COG3775 Phosphotransferase system, galactitol-specific IIC component.
 
    0.765
SRA_06611
Lactose phosphotransferase system repressor; COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.734
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.713
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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