STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRA_07146COG0695 Glutaredoxin and related proteins. (74 aa)    
Predicted Functional Partners:
NrdE
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.994
NrdI
Flavoprotein NrdI; COG1780 Protein involved in ribonucleotide reduction; Belongs to the NrdI family.
 
  
 0.892
nrdF
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
  
 0.854
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.769
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.711
SRA_03076
COG1780 Protein involved in ribonucleotide reduction; Belongs to the NrdI family.
  
  
 0.576
AcnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
  
 0.572
SRA_07136
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.553
SRA_07131
COG0538 Isocitrate dehydrogenases.
  
  
 0.533
SRA_08726
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
  
 0.508
Your Current Organism:
Streptococcus ratti
NCBI taxonomy Id: 699248
Other names: S. ratti FA-1 = DSM 20564, Streptococcus ratti DSM 20564, Streptococcus ratti DSM 20564 = FA-1, Streptococcus ratti FA-1, Streptococcus ratti FA-1 = DSM 20564
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