Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KPN30307.12'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (192 aa)    
Predicted Functional Partners:
KPN30305.1
Hypothetical protein.
       0.866
KPN30306.1
Photosystem I assembly protein Ycf3.
  
    0.846
KPN30078.1
Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
     0.574
rtcB
tRNA-splicing ligase RtcB; Belongs to the RtcB family.
 
   
 0.548
KPN30308.1
Hypothetical protein.
       0.543
ef1b
aEF-1beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
      
 0.542
dacZ
DisA bacterial checkpoint controller nucleotide-binding protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
     0.533
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
     
 0.530
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
       0.491
rpl31e
Hypothetical protein; L34; Belongs to the ribosomal protein L31e family.
       0.491
Your Current Organism:
Halolamina pelagica
NCBI taxonomy Id: 699431
Other names: CGMCC 1.10329, H. pelagica, Halobacteriaceae archaeon TBN21, Halobacteriaceae archaeon TBN49, Halolamina pelagica Cui et al. 2011, JCM 16809, strain TBN21
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