SDE00973.1 protein (Rhodospira trueperi) - STRING interaction network

Nodes:

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SDE00973.1

TRAP transporter, 4TM/12TM fusion protein. (671 aa)

Predicted Functional Partners:

SDE01032.1

0.967

SDD95719.1

0.866

SDE17158.1

0.826

SDE61973.1

0.826

SDE01001.1

0.801

SDE87445.1

0.558

Your Current Organism:

Rhodospira trueperi

NCBI taxonomy Id: 69960
Other names: ATCC 700224, R. trueperi, strain 8316

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDD95719.1	SDE00973.1	SAMN05421720_102187	SAMN05421720_102355	Hypothetical protein.	TRAP transporter, 4TM/12TM fusion protein.	0.866
SDE00973.1	SDD95719.1	SAMN05421720_102355	SAMN05421720_102187	TRAP transporter, 4TM/12TM fusion protein.	Hypothetical protein.	0.866
SDE00973.1	SDE01001.1	SAMN05421720_102355	SAMN05421720_102356	TRAP transporter, 4TM/12TM fusion protein.	Hypothetical protein.	0.801
SDE00973.1	SDE01032.1	SAMN05421720_102355	SAMN05421720_102357	TRAP transporter, 4TM/12TM fusion protein.	Hypothetical protein.	0.967
SDE00973.1	SDE17158.1	SAMN05421720_102355	SAMN05421720_10450	TRAP transporter, 4TM/12TM fusion protein.	TRAP transporter solute receptor, TAXI family.	0.826
SDE00973.1	SDE61973.1	SAMN05421720_102355	SAMN05421720_10934	TRAP transporter, 4TM/12TM fusion protein.	Hypothetical protein.	0.826
SDE00973.1	SDE87445.1	SAMN05421720_102355	SAMN05421720_11497	TRAP transporter, 4TM/12TM fusion protein.	TRAP transporter solute receptor, TAXI family.	0.558
SDE01001.1	SDE00973.1	SAMN05421720_102356	SAMN05421720_102355	Hypothetical protein.	TRAP transporter, 4TM/12TM fusion protein.	0.801
SDE01001.1	SDE01032.1	SAMN05421720_102356	SAMN05421720_102357	Hypothetical protein.	Hypothetical protein.	0.705
SDE01032.1	SDE00973.1	SAMN05421720_102357	SAMN05421720_102355	Hypothetical protein.	TRAP transporter, 4TM/12TM fusion protein.	0.967
SDE01032.1	SDE01001.1	SAMN05421720_102357	SAMN05421720_102356	Hypothetical protein.	Hypothetical protein.	0.705
SDE17158.1	SDE00973.1	SAMN05421720_10450	SAMN05421720_102355	TRAP transporter solute receptor, TAXI family.	TRAP transporter, 4TM/12TM fusion protein.	0.826
SDE61973.1	SDE00973.1	SAMN05421720_10934	SAMN05421720_102355	Hypothetical protein.	TRAP transporter, 4TM/12TM fusion protein.	0.826
SDE61973.1	SDE87445.1	SAMN05421720_10934	SAMN05421720_11497	Hypothetical protein.	TRAP transporter solute receptor, TAXI family.	0.478
SDE87445.1	SDE00973.1	SAMN05421720_11497	SAMN05421720_102355	TRAP transporter solute receptor, TAXI family.	TRAP transporter, 4TM/12TM fusion protein.	0.558
SDE87445.1	SDE61973.1	SAMN05421720_11497	SAMN05421720_10934	TRAP transporter solute receptor, TAXI family.	Hypothetical protein.	0.478

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.926

expected number of edges:

12

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006006

Glucose metabolic process

6 of 12

2.19

3.99

3.96e-09

GO:0006096

Glycolytic process

5 of 8

2.29

3.67

4.16e-08

GO:0005975

Carbohydrate metabolic process

8 of 222

1.05

1.19

2.76e-06

GO:1901575

Organic substance catabolic process

6 of 137

1.14

1.16

7.46e-05

GO:0006094

Gluconeogenesis

2 of 6

2.02

1.13

0.0070

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016620

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

4 of 21

1.78

1.6

0.00040

GO:0050661

NADP binding

3 of 14

1.83

1.25

0.0031

GO:0051287

NAD binding

3 of 23

1.61

0.98

0.0089

GO:0016861

Intramolecular oxidoreductase activity, interconverting aldoses and ketoses

2 of 8

1.89

0.7

0.0483

GO:0003824

Catalytic activity

11 of 1707

0.3

0.23

0.0483

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1047

0.48

0.36

0.0059

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:941

Pentose phosphate pathway, and Glyceraldehyde/Erythrose phosphate dehydrogenase family

10 of 25

2.1

6.46

2.44e-17

CL:943

Glycolysis, and Glyceraldehyde/Erythrose phosphate dehydrogenase family

8 of 13

2.28

6.22

1.78e-14

CL:947

Glyceraldehyde 3-phosphate dehydrogenase, active site, and Glycolysis

5 of 5

2.5

4.32

3.77e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00010

Glycolysis / Gluconeogenesis

9 of 37

1.88

4.81

1.92e-14

map01200

Carbon metabolism

11 of 95

1.56

3.53

1.67e-15

map00030

Pentose phosphate pathway

5 of 24

1.81

2.7

3.99e-07

map01120

Microbial metabolism in diverse environments

11 of 248

1.14

1.7

1.42e-11

map01230

Biosynthesis of amino acids

7 of 123

1.25

1.61

6.54e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

9 of 849

0.52

0.33

0.0339

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

5 of 8

2.29

3.74

2.81e-08

KW-0312

Gluconeogenesis

2 of 4

2.19

1.01

0.0134

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02800

Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

3 of 3

2.5

1.95

0.00024

PF01081

KDPG and KHG aldolase

2 of 2

2.5

1.02

0.0136

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020831

Glyceraldehyde/Erythrose phosphate dehydrogenase family

3 of 3

2.5

1.73

0.00062

IPR020829

Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain

3 of 3

2.5

1.73

0.00062

IPR020828

Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain

3 of 3

2.5

1.73

0.00062

IPR013785

Aldolase-type TIM barrel

4 of 48

1.42

1.01

0.0046

IPR020830

Glyceraldehyde 3-phosphate dehydrogenase, active site

2 of 2

2.5

1.01

0.0144

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00846

Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain

3 of 3

2.5

2.29

5.17e-05

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