STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDX29961.1Cl-channel voltage-gated family protein. (600 aa)    
Predicted Functional Partners:
CDX29963.1
Transcriptional regulator, MarR family.
 
     0.891
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.867
gltB
Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.843
guaA
GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
    
 0.836
CDX37319.1
Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.802
CDX36469.1
Multi-sensor hybrid histidine kinase.
  
 
 0.765
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.732
kdsD
D-arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily.
    
 0.721
CDX37875.1
Putative sensor/response regulator hybrid protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
 0.703
CDX34540.1
Hybrid sensory histidine kinase (fragment).
    
 0.693
Your Current Organism:
Mesorhizobium plurifarium
NCBI taxonomy Id: 69974
Other names: CIP 105884, JCM 21566, LMG 11892, LMG:11892, M. plurifarium, Mesorhizobium sp. LMG 11892, NBRC 102498, Rhizobium sp. LMG 7836, Rhizobium sp. LMG 7854
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